Doctor's Best - Fully Active Folate - Quatrefolic®

  • Features Quatrefolic®, natural form of folic acid
  • Pregnancy, immune system & nerves
  • 5-MTHF methylfolate
  • 400 mcg per capsule
  • 90 capsules
Out of stock
EUR 17.20
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  • Questions about this product? Call +3124 - 663 53 66 or chat with us

Natural Folic Acid - Methylfolate by Doctor's Best

Methylfolate with Quatrefolic® is a very stable, natural form of folic acid that is optimally absorbed by the body. This B vitamin, vitamin B11, is very essential for all kinds of bodily processes. It benefits pregnant women because it contributes to the growth of the unborn child, it has a beneficial effect on the immune system, on the production of blood cells, on cell renewal, it supports fatigue and stress, and it contributes to a normal homocysteine ​​metabolism. In some countries, folic acid is called vitamin B9.

Quatrefolic® methylfolate is stable

Folic Acid, Folate, and Quatrefolic® Methylfolate (5-MTHF) are different forms of Vitamin B11 often confused by consumers and even by medical or nutrition professionals. However, absorption within the body is different, and so are the effects on the body.


  • Folic acid contributes to the formation of the placenta
  • Folic acid contributes to the growth of the unborn child
  • Folic acid contributes to resilience to stress
  • Folic acid contributes to normal psychological functioning
  • Folic acid contributes to the reduction of fatigue
  • Folate contributes to normal amino acid synthesis
  • Folic acid supports the immune system
  • Folic acid supports the production of red and white blood cells
  • Folic acid contributes to the process of cell renewal
  • Folic acid contributes to normal homocysteine metabolism
  • Does not contain gluten; GMO-free
  • Suitable for vegans and vegetarians

What is the difference between folic acid and folate?

Folic acid, or pteroylmonoglutamic acid, is the synthetic, oxidized form of the natural though unstable folate (tetrahydrofolate). Folate is found in food and is used by the body. Folic acid is very stable and is therefore widely used in dietary supplements. Folic acid must be converted in the body across several steps before it can be used. First it is converted into tetrahydrofolate and then, via a methylation cycle, into the active form of 5-methyltetrahydrofolate (5-MTHF). This enzyme requires certain enzymes: the so-called MTHFR enzyme activity. Quatrefolic® methylfolate (5-MTHF) can support this activity. The body can therefore directly use this active form of B11. Quatrefolic® is a very stable form of folate with a high bioavailability.

During pregnancy or family planning, and for the elderly

Doctor's Best Methylfolate from Doctor's Best contains only natural methylfolate from the Quatrefolic® brand. Due to its safety profile and excellent absorption, this product is very suitable for target groups with an increased need for folic acid / folate, including women who want to become pregnant, women who are already pregnant, as well as elderly.

5-MTHF is an important methyl donor

5-MTHF is an important source of the body for what are called methyl groups (CH3). Methyl groups are essential in a process called methylation, which happens continuously in every cell in the body. Methylation is a controlled transfer of a methyl group (CH3: one carbon and three hydrogen atoms) to proteins, amino acids, enzymes and DNA. Via methylation, the functioning of the body is regulated through numerous biochemical processes and metabolic pathways. Thus, 5-MTHF methyl groups are essential for numerous life processes throughout the body.

Guaranteed 6 (S) -5-methyltetrahydrofolate

Folate can be found on the market under various names in various supplements. However, only the L and 6 (S) forms are bioactive. The D and 6 (R) forms are not bioactive. Doctor's Best Methylfolate with Quatrefolic® contains the active form of 6 (S)-5-methyltetrahydrofolate.

About Doctor's Best

Doctor's Best produces high-quality food supplements based on scientific research into good nutrition. The raw materials for the products are grown, developed and researched worldwide. Doctor's Best works together with nutrition scientists to produce strictly high-quality, highly effective supplements. Only branded raw materials are used and supplements have been thoroughly tested during every step of the production process, from raw material to end product. The manufacturing process is integrally based on the Guidelines for Current Good Manufacturing Practice (cGMP). Doctor's Best was founded in 1990 by a physician with an interest in wholesome nutrition. The company’s product range now includes more than 200 items.

Standardized brand products

In its products Doctor's Best almost exclusively uses proprietary and standardized brand materials of official trademarks that have been extensively researched. The authenticity of these ingredients is guaranteed in all products. Doctor's Best never uses alternatives. This results in a qualitatively superior line of supplements with very high bioavailability.

More Information
Product Name
Doctor's Best - Fully Active Folate - Quatrefolic®
Doctors Best
90 capsules
User Instructions

Take 1 capsule daily, preferably between meals, or as recommended by a healthcare practitioner.

Ingredients per Serving

40 mg Vitamin C (as Ascorbic Acid) 50% *, 400 mcg DFE (Dietary Folate Equivalent) Folic Acid (from Quatrefolic® (6S)-5-methyltetrahydrofolic acid, Glucosamine Salt) 200% *.

EU Norm
*RDA = Recommended Daily Allowance
Other Ingredients

Microcrystalline cellulose, modified cellulose (vegetable capsule).

Vegan, Vegetarian
Storage: see label. Keep out of the reach of children. Consult an expert before use in case of pregnancy, breastfeeding, illness or medication.
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