A Dutch mention from 1685
In 1685, Simon van der Stel, commander of the VOC's Cape Colony, travelled to Namaqualand. The diary of that expedition contains one of the first European descriptions of kanna. The Dutch colonists called the plant kauwgoed (chewing stuff), because the Khoikhoi chewed the fermented plant. The name still lives on in Afrikaans.
Made in the United States
Doctor's Best uses Zembrin® from the South African company HG&H Pharmaceuticals, made from kanna that is grown together with San communities. The capsule is plant-based and the product is vegan.
Facts about this product
One capsule contains 25 mg Zembrin®, which is also the maximum daily dose. Do not use during pregnancy or breastfeeding, or with antidepressants or anxiety medication, without consulting your doctor. Stop two weeks before surgery.
Calm-Z, Kanna extract with Zembrin® by Doctor's Best
Calm-Z with Zembrin® contains a patented extract of the plant species Sceletium tortuosum. Sceletium tortuosum is a succulent plant from the ice herb family native to South Africa. Also called Kanna, Channa or Chewable, the plant has been used for over 300 years by the San and Khoikhoi tribes, the oldest inhabitants of South Africa. The specific Sceletium tortuosum species from which Zembrin® is made is grown and cultivated in a joint project with the San people.
Patented South African brand Zembrin®
In 2009, the South African company Hg & H Pharmaceuticals Pty Ltd. obtained the first license to market and export the standardized extract of Sceletium tortuosum. The development of this specific extract under the brand name Zembrin® took over 10 years. The extract was ultimately created by a top team of international scientists and doctors. In the U.S. it enjoys GRAS (Generally Recognized As Safe) status, meaning it has been found safe as well as effective.
Benefits
Calm-Z contains the patented kanna extract Zembrin®. Contains no gluten or soy, GMO-free. Suitable for vegans and vegetarians.
Sceletium tortuosum
The Sceletium tortuosum plant contains alkaloids. Alkaloids are among active substances found in many plants. S. tortuosum contains four major alkaloids: mesembrine, mesembrenone, mesembrenol, and mesembranol. Mesembrine and mesembrenone primarily contribute to the efficacy of Doctor's Best’s Calm-Z.
Cautionary note
Not much is known yet about possible interactions of Sceletium tortuosum and prescription medications. Be careful when using SSRIs, MAOIs, benzodiazepines, and medications for cardiovascular disease.
About Doctor's Best
Doctor's Best was founded by a physician in 1990 because of his interest in the scientific basis of wholesome nutrition. The company produces over 200 high-quality nutritional supplements. All products are made from branded raw materials and are carefully tested during every step of the production process, from raw material to finished product. Production takes place on the strict basis of Current Good Manufacturing Practice Guidelines (cGMP). Doctor's Best works with nutrition scientists worldwide to find new, tested ingredients. This results in high-quality end products, developed according to the latest scientific insights.
Standardized brand products
In its products Doctor's Best almost exclusively uses proprietary and standardized brand materials of official trademarks that have been extensively researched. The authenticity of these ingredients is guaranteed in all products. Doctor's Best never uses alternatives. This results in a qualitatively superior line of supplements with very high bioavailability.
