L-Methylfolate 60 capsules.

One plant-based capsule with 1,000 mcg of folate as Quatrefolic® methylfolate, the form the body uses directly.

Why this product?

1,000 mcg folate per capsule

As Quatrefolic® methylfolate, the form the body uses directly

No conversion by MTHFR needed

Plant-based capsule, suitable for vegans

1 per day, 60 capsules per jar

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60 capsules · 60 days · €0.42 per day
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L-Methylfolate - 60 capsules

L-Methylfolate 60 capsules.

Order before 22:00, processed the same day
Free shipping from €85.00
Money-back guarantee
€24,95
€0,41 per serving
Quantity
01 / The story

Folate in the form the body uses.

01, The story
02, Form & figures
03, Ingredients & dosage
04, What we may claim
05, Quality & production
06, Frequently asked questions
Reading time · 5 min

L-Methylfolate by Seeking Health contains 1,000 mcg of folate as Quatrefolic®, the glucosamine salt of (6S)-5-methyltetrahydrofolate. That is the form of folate the body uses directly, without conversion by the MTHFR enzyme. One plant-based capsule per day.

The MTHFR gene

In 1995 researchers described a common variant in the MTHFR gene, which contains the code for the enzyme that converts folate into methylfolate. In people with this variant the enzyme works more slowly. Since then, methylfolate has become one of the best-known supplements in the world of epigenetics.

Made in the United States

Seeking Health has L-Methylfolate made in the United States according to GMP. The folate is Quatrefolic®, a stable glucosamine salt of methylfolate. The capsule is plant-based.

Facts about methylfolate

About one in ten Europeans has two copies of the MTHFR variant C677T. Methylfolate is also the form that is most common in the blood: folate from food and supplements is largely converted into this form.

L-Methylfolate by Seeking Health

Folate contributes to the normal function of the immune system, normal psychological function and normal blood formation. In addition, folate contributes to the reduction of tiredness and fatigue and has a role in the process of cell division.

Folate as bioavailable L-methylfolate

Folate from food must first be converted into an active form before your body can use it, however. Your MTHFR enzyme converts folate from food into the active form of folate, L-methylfolate, or, in biochemical terms, L-5-MTHF. Due to genetic variations, this conversion is not always optimal. L-5-MTHF bypasses the MTHFR enzyme and therefore works independently of these known variations. This Seeking Health product contains Quatrefolic®, a high-quality form of 5-MTHF. Folate as bioavailable L-methylfolate is easily absorbed and usable by cells, the most common form of folate in the bloodstream and the only form of folate that can cross the blood-brain barrier.

Benefits

Folate contributes to the normal function of the immune system. Folate contributes to the reduction of tiredness and fatigue. Folate contributes to normal psychological function. Folate contributes to normal homocysteine metabolism. Folate contributes to normal amino acid synthesis. Folate contributes to normal blood formation. Folate has a role in the process of cell division. Folate contributes to maternal tissue growth during pregnancy. Health claims permitted in the EU.

Suitable for

This product is suitable for bariatric patients (stomach reduction surgery), pregnant women, breastfeeding women, vegetarians, vegans and children aged 4 and over. This product contains no dairy, eggs, fish, shellfish, nuts, peanuts, wheat, soy, sesame, gluten, GMOs, artificial colourings or artificial flavourings.

About Seeking Health

From an early age, Ben Lynch, founder of Seeking Health, has been interested in the relationship between health and gene expression, and he studied naturopathy, molecular biology and epigenetics, among other subjects. In his book Dirty Genes, he describes how the cause of numerous health problems may lie in having “dirty” genes and shows how you can optimise the functioning of your genes through the right diet and lifestyle. In recent years, he has helped thousands of clients, doctors and healthcare professionals apply these insights and is currently the most consulted expert in the field of epigenetics.

02 / Form & figures

Figures from the label.

Per capsule, the daily dose as stated by Seeking Health.

1,000 mcg
Methylfolate
As Quatrefolic®, 1,700 mcg DFE.
500%
Of the RI
Reference intake for folate 200 mcg.
1
Capsule per day
With or without food.
60
Capsules
60 days at 1 per day.
Ingredients and use

Per daily dose, 1 capsule.

Per capsule Amount %RI Form
Folate 1,000 mcg (1,700 mcg DFE)500% Quatrefolic® methylfolate

Label · other ingredients: microcrystalline cellulose, plant-based capsule (hypromellose, water), ascorbyl palmitate, L-leucine, silicon dioxide · dosage: 1 capsule per day with or without food, not within 5 hours of bedtime · net contents 60 capsules · RI = reference intake

Product information

How to use it. And everything on the label.

How to use

  1. 1

    Take 1 capsule as needed, with or without food.

  2. 2

    Do not take within 5 hours of bedtime, as it may interfere with sleep.

  3. 3

    Store in a cool, dry place with the lid closed, out of reach of children.

Contents
60 capsules
Allergens
-
Other ingredients
Microcrystalline cellulose, vegetarian capsule (hypromellose and water), ascorbyl palmitate, l-leucine and silicon dioxide
Storage
Store in a cool, dry and dark place.
Do not exceed the recommended daily dose.
Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle.
Keep out of the reach of young children.
* RI = reference intake according to European standards.

Reviews

What we may claim

Claims for folate.

Framework
EU 432/2012
EFSA register
Subject
Folate
(1,000 mcg per capsule)

In Europe, we may only make health claims about food supplements that have been assessed and authorised by the EFSA and are listed in the official EU register.

At 1,000 mcg per capsule, folate is well above the threshold. Below are all eight authorised claims for folate.

Folate contributes to the normal function of the immune system.

EFSA · AUTHORISED HEALTH CLAIM

Folate contributes to the reduction of tiredness and fatigue.

EFSA · AUTHORISED HEALTH CLAIM

Folate contributes to normal psychological function.

EFSA · AUTHORISED HEALTH CLAIM

Folate contributes to normal homocysteine metabolism.

EFSA · AUTHORISED HEALTH CLAIM

Folate contributes to normal amino acid synthesis.

EFSA · AUTHORISED HEALTH CLAIM

Folate contributes to normal blood formation.

EFSA · AUTHORISED HEALTH CLAIM

Folate has a role in the process of cell division.

EFSA · AUTHORISED HEALTH CLAIM

Folate contributes to maternal tissue growth during pregnancy.

EFSA · AUTHORISED HEALTH CLAIM
AND WHAT WE ARE NOT ALLOWED TO SAY
  • -
    No claim whatsoever about curing, preventing or treating diseases. A supplement is not a medicine and we do not present it as one.
  • -
    No substitute for medical advice. If you take medication, are pregnant or have a medical condition, consult your doctor.
  • -
    No substitute for a varied diet. A supplement is an addition to healthy eating, not an alternative.
AWAITING ASSESSMENT

A scientific assessment by the EFSA is still ongoing for a number of plant substances. Claims for these may be used under a transitional arrangement and are marked on this page as on hold.

Professionally reviewed

Read and checked by a fellow professional.

Diederik Jansen

Independent researcher · editorial review

The content of this page has been checked for factual accuracy, from the composition to compliance with the European rules on health claims.

The content of this page has been checked for factual accuracy, from the composition to compliance with the European rules on health claims.

Curator's note
Methylfolate in a simple capsule, without additions.
Selected by Ergomax

One capsule with 1,000 mcg of methylfolate as Quatrefolic®. Preferably take it in the morning. If you do not tolerate methylfolate well, choose Folinic Acid.

About the brand

Seeking Health, briefly explained.

Seeking Health

Nutrition that fits your genes.

Seeking Health was founded by Ben Lynch, naturopathic doctor and author of Dirty Genes. He studied at Bastyr University in Washington and has worked for years with doctors and health professionals who apply insights from epigenetics. His starting point: your genes are not a fixed fate, and with diet and lifestyle you can work with them. Seeking Health is best known for active forms of vitamins, such as methylfolate and methylcobalamin, and for methyl-free variants for those who are sensitive to them.

All products from Seeking Health
Quality and production

Active forms, clear choices.

Seeking Health opts for vitamins in the form in which the body uses them and offers a methyl-free variant of many formulas. The products are made in the United States according to GMP and are free of the most common allergens. Some of the raw materials are branded ingredients, such as Quatrefolic® (methylfolate) and MecobalActive® (methylcobalamin).

Forms 01
Active vitamins
Such as Quatrefolic® and MecobalActive®
Choice 02
Methyl or methyl-free
MF variants without methyl groups
Purity 03
Without common allergens
No gluten, dairy or soy
Production 04
Made in the USA
According to GMP
08 / Frequently asked questions

What you still wanted to know.

Folate from food and folic acid must first be converted in the body by the MTHFR enzyme. Methylfolate is already the end form and does not have to go through that step. This is particularly relevant for people in whom this enzyme works more slowly because of a genetic variant.

Take 1 capsule per day, with or without food. Do not take it within 5 hours of bedtime, as it can disturb sleep. If you are pregnant or trying to conceive, discuss with your midwife or doctor which dosage of folate suits you.

There are no allergens on the label. The product is free of dairy, egg, fish, shellfish, nuts, peanut, wheat, soy, sesame and gluten and the capsule is plant-based. Keep the jar closed in a cool, dry place out of the reach of children.

A patented form of methylfolate: (6S)-5-methyltetrahydrofolate as a glucosamine salt. This form is stable and dissolves well in water.

DFE stands for dietary folate equivalents. Because folate from a supplement is absorbed better than folate from food, 1,000 mcg methylfolate equals 1,700 mcg DFE. It is the same dose, expressed differently.

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09 / Combines well with

A routine, not a single product.

The body needs vitamin B12 to be able to use methylfolate. That is why you complement methylfolate with a B12.

Seeking Health L-Methylfolate, jar of 60 capsules
L-Methylfolate
Hydroxo-Adeno B12 lozenges – pack of 60 tablets
Hydroxo-Adeno B12
Folate and B12

Methylfolate and B12 together.

  • Folate contributes to normal homocysteine metabolism
  • Vitamin B12 contributes to normal homocysteine metabolism
The claims mentioned are authorised by the EFSA and apply at the recommended daily dosage.
€54,90

L-Methylfolate €24,95 + Hydroxo-Adeno B12 €29,95